翻訳と辞書
Words near each other
・ Notes on Linguistics
・ Notes on Muscovite Affairs
・ Notes on Nationalism
・ Notes on Novelists
・ Notes on Nursing
・ Notes on Ornette
・ Notes on Prosody
・ Notch 2
・ Notch 3
・ Notch code
・ Notch Lake
・ Notch Mountain Trail
・ Notch of Rivinus
・ Notch Peak
・ Notch Peak Formation
Notch proteins
・ Notch signaling pathway
・ Notchback
・ Notched triplefin
・ Notchheaded marblefish
・ Notchietown, Oklahoma
・ Notching
・ Notching of the ribs
・ Notchko, California
・ Notchlip redhorse
・ NotchUp
・ Notchview
・ NotCompatible
・ Notcutt v Universal Equipment Co (London) Ltd
・ Notcutts


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Notch proteins : ウィキペディア英語版
Notch proteins
__NOTOC__
Notch (DSL) proteins are a family of transmembrane proteins with repeated extracellular EGF domains and the notch (or DSL) domains. These proteins are involved in lateral inhibition in embryogenesis.
The Notch signaling network is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells. In ''Drosophila'', Notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. This same pathway operates to mediate binary cell fate decisions in ''C. elegans'' development. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4853 )
==Human proteins containing this domain ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Notch proteins」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.